The CDR‐SB was used as a global measure for AD dementia progression. 11 , 12 IADLs were assessed with the Functional Activities Questionnaire (FAQ) 24 from the UDS in which the study partner rates the participant's current ability to perform accustomed activities relative to their previous ability to do so. The rating choices are: “performs normally” (scored as 0), “has difficulty but does it by themselves” (scored as 1), “requires assistance” (scored as 2), or “dependent” (scored as 3). In addition, there is an unscored “not applicable” category for participants who were unaccustomed to doing a particular activity. Based on studies of outcomes of interest to patients and their caregivers, 15 , 16 we selected 4 of the 10 activities in the FAQ as indicative of activities that represent independent living: (1) managing personal finances (e.g., paying bills, keeping financial records), (2) driving a motor vehicle or arranging travel outside of the home, (3) remembering to take medications and to keep appointments, and (4) preparing a balanced meal. We defined loss of independence in IADLs as a score of 2
