For females, Ctss and Il1rn null mice showed slightly reduced preference for saccharin whereas Ctsf knockout mice demonstrated slightly increased preference for the sweet taste. Total fluid intake was reduced in Ctss and Il1rn null female mice and increased in Cd14 knockout females. Similar to male mice, only Ctss null female mice showed reduced avoidance (increased preference) for quinine. Total fluid intake was reduced in B2m, Ctss and Il1rn null females and increased in Cd14 and Il6 knockout female mice (for complete results see Supplemental Table 4; for detailed statistics see Supplemental Table 6).