for each SNP: those homozygous for the more frequent allele and “carriers” of the less frequent allele who were heterozygous and homozygous for that allele. For SNP-1, subjects were divided into those homozygous for G allele and “A carriers” with AA or AG genotypes; for SNP-2, divided into those homozygous for C and “T carriers” with TT or TC genotypes; for SNP-3, divided into those homozygous for C and “A carriers” with AA or AC genotypes; and for SNP-4, divided into those homozygous for C and “T carriers” with TT or TC genotypes. Sample characteristics by genotype are shown in Table 1.