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Chunk #18 — Results — Previously published POAG genes

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Genome-wide association study of primary open angle glaucoma risk and quantitative traits.
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We found no association evidence for SNPs within MYOC, as expected, since patients with MYOC mutations were excluded. Also MYOC mutations along with WDR36 and OPTN are rare causes of POAG and thus not expected to be detected by GWAS. We found some very weak evidence in OPTN (p=0.02), but none in WDR36.