2004; Thomas and Hagan, 2004; Cifariello et al., 2008; Eriksson et al., 2008]. Pharmacologically, 5-HT7 receptors have a high affinity for a number of antidepressants and antipsychotics, such as clozapine and risperidone [Roth et al., 1994], underscoring their potential role in the neurophysiology of psychiatric disorders. However, to date, purported human disease relationships with 5-HT7 have been limited to schizophrenia [Ikeda et al., 2006].
