We compared top SNP associations from the PTSD case-control and PCL-Total results against the largest available external PTSD dataset, from the PGC-PTSD13. For the EUR case-control phenotype, there was nominal replication for one of three SNPs: for rs7680*A nearest to MAD1L1, with a log(OR) of −0.0712 (s.e. 0.013, P = 4.17 × 10−8) in MVP and a log(OR) of −0.0639 (s.e. 0.0215, P = 0.00312) in PGC-PTSD. For the EUR PCL-Total symptom scores, there were six of 15 possible nominal replications (Supplementary Table 6).
