Three SNPs (rs1799971(#5), rs510769 (#6) and rs3778151 (#8)) were genotyped using the Illumina custom array.9 Additional five tag SNPs were selected for genotyping from the 100 kb 5′ flanking region (blocks 1: rs1551808 (#1), rs7758009 (#2), and rs7760028 (3#), and block 4: rs1074287 (#4)), and intron 1 (block 4: rs3778146 (#7)) (Table 1, Figure 1, and Supplement Table 1). The selection was based on information from HapMap, chromosomal location and frequency (MAF> 0.1 in CEU).
