LOC339975 shows homology only with sequences from other primates. In order to assess the potential functional impact of alleles at rs11726136, we therefore tested AD case and control post-mortem tissue from PFC and NAc for differences in LOC339975 expression by clinical status or genotype. The final numbers available for analysis were for PFC, 28 cases and 30 controls and 50 reference allele T/T and 5 T/G genotypes, and for NAc, 34 cases and 35 controls and 58 T/T and 7 T/G genotypes (Supplementary Table S7).
