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Chunk #41 — 4. Discussion

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Changes in gene expression within the extended amygdala following binge-like alcohol drinking by adolescent alcohol-preferring (P) rats.
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In the CeA, there were some common biological systems that overlap between the present study and the adult study (McBride et al., 2010), these included neuroactive ligand-receptor interaction (Table 3), neuron projection morphogenesis (Table 3) and positive regulation of cell component organization (Table 3). In the adult, the genes associated with neuron projections and regulation of cell organization were mainly up-regulated suggesting an overall positive effect of binge drinking on these biological systems.