To determine the genotypic effects of the Lwt/+ mutation, statistical analyses were performed on all body weights, NA, NT and femur lengths, organ weights, TF, and food and water intakes by fitting two linear models. The first model accounted for the effects of genotype (Gi) and only included age at sacrifice as a covariate (the range of age at sacrifice was 14 days): yijl = a(Gi) + Agej + eijkl [Model 1]. The second model accounted for genotype and used age and SACW as covariates: yijkl = a(Gi) + Agej + SACWk + eijkl [Model 2] to determine if changes in body length and body composition were simply due to the size of the mouse.
