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Chunk #0 — 1. Introduction

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Peroxisome proliferator-activated receptor and retinoic x receptor in alcoholic liver disease.
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Alcoholic liver disease, which includes a spectrum of liver injury that covers from the relatively benign alcoholic fatty liver to the potentially fatal alcoholic hepatitis and cirrhosis, has a known etiology but a complex pathogenesis resulting from a combination of genetic, environmental, nutritional, metabolic, and more recently, immunologic factors as well as cytokines [1–4].