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Chunk #1 — 1. Introduction

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Peroxisome proliferator-activated receptor and retinoic x receptor in alcoholic liver disease.
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Fatty liver is the most frequent hepatic abnormality found in alcoholics as a toxic manifestation of ethanol ingestion. Fatty liver may occur alone or be part of the picture of alcoholic hepatitis or cirrhosis and the development of these late alterations is not clearly understood.