Study participants (Table 1) included 43 patients at clinical high risk (CHR) for psychosis based on the Structured Interview for Prodromal Syndromes (SIPS; Miller et al., 2002), 19 young patients with DSM-IV schizophrenia (YSZ) based on the Structured Clinical Interview for DSM-IV (SCID), and 42 healthy control (HC) subjects. CHR patients met criteria for at least one of the three sub-syndromes defined by the COPS (Miller et al., 2002): 1) Attenuated Positive Symptoms (APS), 2) Brief Intermittent Psychotic States (BIPS), and/or 3) Genetic Risk with Deterioration in social/occupational functioning (GRD). Interviews were conducted by a trained research assistant, psychiatrist, or clinical psychologist.
