paperKB
coga / coga-kb
Help
Sign in

Chunk #19 — Results — Single SNP association

Source
Genome-wide association study in obsessive-compulsive disorder: results from the OCGAS.
Embedded
yes

Text

it is of note that, for the region around DLGAP1 an independent SNP in our analyses (rs3866988) yielded a P-value of 2.67×10−4 and thus indicating this region as a susceptibility factor for OCD (r2=0.023, D′=0.316 between rs3866988 and rs11081062/ rs11663827, based on 1 000 genomes data). It is also of note, that 12 out of 15 markers (counting the DLGAP1 markers in perfect LD only once) show the same direction of effects for the effect alleles in both the IOCDF-GC and OCGAS analyses (binominal test with probability 0.5 = sign test: P=0.0176). Detailed results for the follow-up of the IOCDF-GC results are found in Table 2.