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Chunk #19 — Results — Lightweight heterozygotes consume more ethanol than wild types and establish conditioned place preference to ethanol

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Conserved role of unc-79 in ethanol responses in lightweight mutant mice.
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relative to +/+ mice in preference for ethanol [F1,112(genotype) = 0.35, P = 0.56] or consumption of ethanol [F1,112(genotype) = 0.40, P = 0.53] (Figure 7B and 7D). Further, there were no alterations in taste sensitivity in Lwt/+ mice relative to +/+ littermates for either preference [F1,26(genotype) = 0.23, P = 0.65] or consumption [F1,26(genotype) = 0.22, P = 0.64] of saccharin-containing solutions over water (Figure 8A and 8B) or preference [F1,26(genotype) = 0.74, P = 0.40] or consumption [F1,26(genotype) = 2.1, P = 0.16] of quinine-containing solutions over water (Figure 8C and 8D). Additionally, no differences in taste sensitivity were observed in the control strain (D.C. and D.J.S., data not shown).