Chunk #38 — Results — Question 2: Is Our Behaviorally Based Construct of Disinhibition Meaningfully Related to Laboratory-Based Measures of Response Inhibition?
We used phenotypic analyses to specify the extent of the relationship between behavioral disinhibition at each age and executive functions at age 17. To examine the discriminant validity for response inhibition, we also examined whether behavioral disinhibition was more strongly related to response inhibition than two other executive functions (working memory updating and task-set shifting) that have been shown to be behaviorally and neuropsychologically related but separable from response inhibition (Collette et al., 2005; Friedman et al., 2006; Miyake, Friedman, et al., 2000; Sylvester et al., 2003; Willcutt et al., 2001). Using confirmatory factor models (separately for the Wave 1 and Wave 2 behavioral disinhibition data), we estimated the phenotypic correlations among the four latent factors. Models were fit to pedigree data in Mx to accommodate the nonindependence of the data due to the twin correlations.