Overall, the internalizing dimension has received less attention in studies of children and adolescents with familial risk for alcohol dependence, with most studies assessing the externalizing dimension exclusively (Krueger et al., 2002; Krueger et al., 2005; Hicks et al., 2007; Carlson and Iacono, 2008). Inclusion of assessment for internalizing disorders would appear warranted in view of the clear indication that the presence of depression is associated with reduction of P300 amplitude in adults (Bruder et al., 1995; Blackwood et al., 1987; Diner et al., 1985; Yanai et al., 1997; Gangadhar et al., 1993; Roschke and Wagner, 2003).
