Chunk #5 — Materials and Methods — Genotyping, quality control and imputation

Source

Genome-Wide Association Study Meta-Analysis of the Alcohol Use Disorders Identification Test (AUDIT) in Two Population-Based Cohorts.

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Genotype imputation was performed on 487,409 individuals by the UKB team using IMPUTE4 (18) and the Haplotype Reference Consortium reference panel. After quality control, 16,213,998 SNPs remained for GWAS analyses. Additional details on genotyping and quality control are shown in the Supplementary Material.