Rates of substance use in the Spit for Science sample are consistent with other large studies of college-age populations. For example, in Spit for Science 72% of participants report having tried alcohol, compared to 71% in the Monitoring the Future (MTF) post 12th grade assessment (Johnston et al., 2010); the prevalence of marijuana use is 41% in Spit for Science and 44% in MTF (additional details in Dick et al., 2014). In initial analyses we examined patterns of substance use and potential changes in those patterns across the transitional first year of college by conducting a latent class analysis of substance use as reported at the beginning of the fall freshman semester, and midway through the spring semester (Cho et al., under review). At both timepoints, three classes of individuals emerged: (1) polysubstance users, with relatively higher levels of use of alcohol, tobacco, cannabis, and other illicit drugs (2) alcohol, tobacco, cannabis users; and (3) low substance users, with overall low levels of use, with alcohol use being the most common. Interestingly, very few participants transitioned in their substance use