Chunk #21 — Results — Phenotypic analyses — Twin correlations

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Most of the genetic covariation between major depressive and alcohol use disorders is explained by trait measures of negative emotionality and behavioral control.

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Table 2 displays the within-trait and cross-trait twin correlations. Inspection reveals that the within-trait MZ correlations were larger than the DZ correlations for MDD, AUD, SR, and CON, which implicates genetic influences for all of the phenotypes studied. In addition, the cross-trait MZ correlations were larger than the DZ correlations for MDD, AUD, SR, and CON, which implicates genetic influences on the covariation between these traits.