Processing of samples, genotyping, QC and imputing was done in 23 waves. In this study individuals from the first four waves were excluded as only a few cannabis use disorder cases were present in these waves (range 0-15 cases). The waves represent approximate birth years and the four waves that were excluded represent to a large extend individuals, which in 2013 (the time of extraction of register diagnoses) were children. Mean age of cases is 24,77 years (standard deviation =5.32) and mean age of controls is 22,67 years (standard deviation =3.86). The control group is younger and the age span wider than for the cases. The presence of younger individuals among the controls could reduce power since some controls eventually will become cases, and it also reduces the risk of discovering a false positive association.
