presence of mental disorders. Only 54 individuals had a diagnosis of CUD and anorexia, and all individuals having a diagnosis of anorexia among cases and the control group were excluded. After QC the study included 2,387 cases and 48,985 in the control group. Supplementary Table 1 gives an overview of the distribution of individuals with a psychiatric disorder among the CUD cases and the control group. None of the comorbid psychiatric disorders deviated with respect to the distribution of individuals over CUD diagnosis sub-categories (Supplementary Table 3).