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Chunk #0 — INTRODUCTION

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Associations of parent-adolescent closeness with P3 amplitude, frontal theta, and binge drinking among offspring with high risk for alcohol use disorder.
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One in 8 US children under the age of 18 live with at least one parent with alcohol use disorder (AUD) or other substance use disorders (SUDs), rendering them at higher risk for developing AUD, SUDs, and other mental health problems (McCance-Katz, 2018). Parents wield both genetic and social-environmental impact on children’s behavior and brain development and can contribute to both risk and resiliency to AUD (Bernier et al., 2012). Ample evidence shows that children of individuals with AUD are four times more likely than other children to develop AUD, emphasizing intergenerational transmission of genetic risk (e.g., Lipari & Van Horn, 2017). Research shows that parenting behaviors are also important in shaping children’s behavior and in the effective development of their brain architecture, functions, and capacity. Across several studies, exposure to childhood maltreatment and poor-quality parenting has been correlated with global changes in brain development as well as changes in circuitries that support higher-level emotional and cognitive functioning (Bick & Nelson, 2016; Teicher et al., 2016). Longitudinal studies have shown that parenting quality during early years is associated with prospective