To aid interpretation, we report findings as linkage disequilibrium (LD) independent SNPs and the corresponding ranges attributed to the LD. LD pruning was performed using the clump flag in PLINK v1.9 [28, 34]. Clumping was used to link additional associated markers within a 0.5Mb window surrounding the primary association. Markers were linked if they were also associated at P < .05 and had an estimated LD with the index SNP of r2 ≥ 0.2. Associated regions were defined for each index SNP as the location spanning all linked markers. All LD statistics were calculated using the 1000 genomes project phase 1 integrated reference haplotypes.
