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Chunk #11 — Methods — Statistical analyses — Association, meta-analyses, and binomial sign test

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Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia.
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Binomial sign tests to evaluate the random direction effect between studies were implemented in STATA (version 13, Statacorp, College Station, TX, USA).