sibling relationships, peer networks, temperament and behaviourDevelopment: puberty and menstruation, speech and language, fine and gross motor coordinationEducation questionnaires and tests administered in school Understanding of mathematics and science (age 8, 11 and 14 years)SpellingSchool experiences and aspirationsTeacher assessment of the child (age 8 and 11 years)‘CiF’ clinical assessment measures [10 clinics (Supplementary Table S1, available as Supplementary data at IJE online), 10% subsample] Physiological: anthropometry, blood pressure and pulse rate, lung function, fitness, skin, eye and dental observations, allergy testing, vision, tympanometry and hearing, speech and languageCognitive: speech and language, cognition (Griffiths test and WPSSIa)‘Focus’ clinical assessment measures [nine clinics from the age of 7–17 years (Supplementary Table S1, available as Supplementary data at IJE online), full ‘eligible sample’ invited, see recruitment earlier in this article] Physiological: anthropometry, blood pressure, bone mineralization, fat and lean mass using DXAa whole body and hip scans, pQCTa leg scan, audiometry and tympanometry, lung function, vision, taste and smell, atopy (skin prick test)Cognitive: IQ (WISCa), motor skills, memory, reading abilityPsychological and social: depression (CIS-Ra), gender behaviour, self-esteem, peer relationships, antisocial activities, romantic relations (ESYTCa), alcohol and drug use, eating disorders aWPPSI: Wechsler Preschool and Primary Scale of Intelligence, DXA: Dual-emission X-ray Absorptiometry bone