paperKB
coga / coga-kb
Help
Sign in

Chunk #4 — Methods — Samples

Source
Using polygenic scores for identifying individuals at increased risk of substance use disorders in clinical and population samples.
Embedded
yes

Text

The FinnTwin12 Study (FT12) is a population-based study of Finnish twins born 1983–1987 identified through Finland’s Central Population Registry. A total of 2705 families (87% of all identified) returned the initial family questionnaire late in the year in which twins reached age 11. Twins were invited to participate in follow-up surveys when they were ages 14, 17, and approximately 22 (during young adulthood). An intensively studies sample was selected as 1035 families, among whom 1854 twins were interviewed at age 14. The interviewed twins were invited as young adults to complete the Semi-Structured Assessment for the Genetics of Alcoholism (SSAGA)19,20 interview (n = 1,347) and provide DNA samples (see Kaprio 2013 for a full description). The current analysis uses data from the young adult wave (mean age = 21.9; range 20–26), which included retrospective lifetime diagnoses.