KEGG analysis of the VTA gene data indicated 11 significant categories containing 6 or more genes each (Table 3), some of which could alter neuronal function. Two categories, steroid biosynthesis and extracellular matrix- (ECM) receptor interaction, are consistent with the results of the GO categories of ‘steroid metabolic process’ and ‘cell adhesion.’ Genes in the category of ‘regulation of actin cytoskeleton’ could influence dendritic structure and function, including synaptic plasticity.
