Ingenuity pathways analysis indicated different networks were altered by ethanol drinking, one of which had clusters around Fos and Srebf1 and a second which had clusters of genes around Nfkb1a (Table 4). There were 16 genes clustered around Fos and 15 genes clustered around Srebf1; 11 of the 16 genes clustered around Fos and 13 of the 15 genes clustered around Srebf1 had lower expression levels in the ethanol group than in the water group. In contrast, 10 of the 14 genes clustered around Nfkb1a had higher expression levels in the ethanol drinking group vs. water controls.
