paperKB
coga / coga-kb
Help
Sign in

Chunk #8 — Methods — Immunohistochemistry

Source
Expression of ZNF804A in human brain and alterations in schizophrenia, bipolar disorder, and major depressive disorder: a novel transcript fetally regulated by the psychosis risk variant rs1344706.
Embedded
yes

Text

Immunohistochemistry was carried out as described in the eAppendix in the Supplement, using the avidin-biotin complex–diaminobenzidine method. Given the findings (see Results), we investigated whether ZNF804A immunoreactivity was affected by schizophrenia or rs1344706 using the sections of inferior parietal lobe (eTable 1 in the Supplement). We focused our analyses on lamina III pyramidal neurons, measuring their density, size, and staining intensity (eAppendix in the Supplement).