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Chunk #17 — Results — Description of discovery and replication samples in relation to smoking behaviors — Replication sample

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Large-scale genome-wide association study of Asian population reveals genetic factors in FRMD4A and other loci influencing smoking initiation and nicotine dependence.
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The average age of the subjects was 40.8 ± 14.8 years for EAs and 39.9 ± 14.6 years for AAs. The average family size was 3.16 ± 0.69 for EAs and 3.10 ± 0.75 for AAs. Of these families, 60.5% had at least one biological parent recruited, 50.4% had two full sibs, and 44.6% had three or more full sibs. If a family had no biological parents recruited, we had at least three full sibs. The average Fagerstrom test for ND (FTND) score was 6.4 ± 2.2 for EA and 6.3 ± 2.1 for AA smokers. The average CPD was 19.8 ± 13.6 for EA and 19.5 ± 13.0 for AA smokers.