(18.0 [0.8]) and 1548 men (17.9 [0.7]). Because offspring had completed multiple longitudinal assessments, we selected measures for the analysis reported here from the assessment that took place closest to their 17th birthday, so long as that assessment was completed when they were between 16.5 and 21 years old. This allowed us to maximize the size of the offspring sample, while ensuring that the sample used in the current analyses was restricted to Caucasian participants, who constitute > 90% of MCTFR participants. Ethnicity was determined from self-reports and information derived from birth records and confirmed using the results from an Eigenstrat analysis (Price et al., 2006) as described in Miller et al. (2012), which also provides additional details concerning the MCTFR GWAS sample.
