Chunk #22 — Results — DNMT3B SNP associations with DNAm and RNAexp

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Genome-wide association study across European and African American ancestries identifies a SNP in DNMT3B contributing to nicotine dependence.

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Beyond the brain tissues in GTEx, rs910083 is associated with RNAexp of other genes within 1 MB (Supplementary Table 6): MAPRE1 (smallest P=7.3×10−17 in sun exposed skin), COMMD7 (smallest P=1.0×10−6 in colon), and BPI fold containing family B, member 2 (BPIFB4, smallest P=5.4×10−5 in artery).