We determined the extent to which the GPS predicted weight and severe obesity in a testing dataset of 288,016 middle-aged participants of the UK Biobank (independent of the 119,951 validation dataset participants studied above). Participant mean age was 57 years and 55% were female. Mean weight was 78.1 kilograms and mean BMI was 27.4 kg/m2. 23.9% of the participants were obese (BMI ≥ 30 kg/m2) and 1.8% met criteria for severe obesity.
