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Chunk #10 — RESULTS — Polygenic susceptibility to weight and severe obesity in middle age

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Polygenic Prediction of Weight and Obesity Trajectories from Birth to Adulthood.
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The GPS approximated a normal distribution in the population (Figure S1). The correlation of the GPS and observed BMI was 0.29, identical to the UK Biobank validation dataset. Correlations were similar when participants were stratified into 5-year age bins, ranging from 0.28 to 0.31 (Table S3).