Chunk #11 — Results — Mega-analysis — Cortical thickness and surface area differences between OCD patients and controls — Adults:

Source

Cortical Abnormalities Associated With Pediatric and Adult Obsessive-Compulsive Disorder: Findings From the ENIGMA Obsessive-Compulsive Disorder Working Group.

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Lower cortical thickness was observed in adult OCD patients (N=1498) compared to controls (N=1436) in the bilateral inferior parietal cortex (Cohen’s d effect size −0.14; Figure 1 and Supplementary Table S4). In all tables, regions are listed in order of effect size (strongest to weakest). A lower surface area was observed in the left transverse temporal cortex (Cohen’s d −0.16; Supplementary Table S5 and Figure S2). None of the regions showed significant sex-by-diagnosis or age-by-diagnosis interaction effects.