Specifically, the U for mash-bmalite includes the 44 singleton configurations (Uk=ekekT), and matrices corresponding to the models in Flutre et al.5, with heterogeneity parameters H = {0, 0.25, 0.5, 1}. (When H = 0, effects are equal in all conditions; when H = 1, effects are independent among conditions.) We used ω = {0.1, 0.4, 1.6, 6.4, 25.6}, similar to the coarse grid used in Flutre et al.5, and chosen to capture the full range of the GTEx (real and simulated) Z statistics.
