whether ongoing PFC activity is aligned with these sequences during periods of high theta coherence is yet to be explored. Since theta coherence emerges after behavioral learning [27], rhythmic and representational coherence could underlie information exchange related to current location and learnt rules, although the causal role of this coherence in memory has also yet to be demonstrated. Intriguingly, inactivating direct connections from the hippocampus to PFC impairs gamma synchrony, but not theta synchrony, in spatial memory tasks [30]. In contrast, theta synchrony is affected during anxiety-related behaviors [67]. This indicates that theta and gamma synchronization may play different roles in cognition and moreover differentially depend on behavioral context.
