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Chunk #14 — Online methods — Meta-analysis of lung cancer GWAS

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Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.
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Conditional analysis was undertaken using SNPTEST where individual level data was available and GCTA32 packages for the previous lung cancer GWAS, with the LD estimates obtained from individuals of European origin for the later. Results were combined using fixed effects inverse variance weighted meta-analysis as described above33.