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Chunk #15 — Online methods — Assessing Statistical Significance

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Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.
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Genome wide statistical significance was considered at P-values of 5 × 10−8 or lower, but we also presented significance per alternative criteria following Bonferroni correction for the number of effective tests or Bayesian False Discovery Probability (BFDP) described below.