show that neurotransmission of both dopaminergic and αβ neurons specifically affected conditioned preference expression, we hypothesize that the manifestation of ethanol reward memory may be mediated by dopaminergic innervation of the αβ neurons. This is in line with recent studies showing that dopaminergic innervation of the α lobe plays a role in conditioned response to shock and the effect of satiety on the conditioned response to sucrose22,23.