Our data did not demonstrate differential expression in spliceosome factors with behavior condition, but indirectly implicated spliceosomal machinery. Specifically, known protein-protein interactions were revealed between Stat92E and spliceosome complex associated proteins, including Cdc5, CG7564, and tsu (Guruharsha et al. 2011) (Figure 4). The lack of differentially expressed splicing factors with treatment condition does not, however, rule out the possibility that spliceosome-associated proteins were acutely affected during treatment exposure. Consequently, our data may represent the aftermath of these, or post-translational response, effects.
