The same approach was taken to re-align data for two tissues from the GTEx Project (Extended Data Fig. 8). Raw fastq-files were obtained from dbGap (accession phs0004242.v6.p1.c1) for Adrenal Gland (N=126 samples) and Esophagus Gastroesophageal Junction (N=127 samples; limited to 126 unique samples used in the GTEx V6p map).