Chunk #15 — Results — Latent Causal Variable Analysis.

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Bi-ancestral depression GWAS in the Million Veteran Program and meta-analysis in >1.2 million individuals highlight new therapeutic directions.

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After filtering for suitable trait pairs with LCV-estimated h2 z-scores≥4, 1,667 phenotypes were powered to evaluate causal estimates relative to MDD-META; no statistically significant putatively causal genetic causality proportions (gĉps) were detected.