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Chunk #0 — Introduction

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Role of overlapping genetic and environmental factors in the relationship between early adolescent conduct problems and substance use in young adulthood.
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Adolescence is a period in which many youth initiate the use of psychoactive substances. To illustrate, between ages 15 and 21, a sharp increase is seen in the incidence of alcohol, tobacco, and cannabis use, with estimates of, respectively, 90, 70, and 25–50 percent in American and European 21-year-olds [1]. Increased levels of substance use are associated with problems later in life, including poor educational performance, health problems and substance use disorders [2–5].