the bias-adjusted ORs have a statistically significant difference from the replication OR estimates. Of the 10 SNPs, 8 bias-adjusted ORs are closer to the replication estimates, the exceptions being rs8034191 and rs1051730, which showed very extreme p-values in the replication stage. Among the 10 SNPs, 8 failed to show significance in the replication cohort. Interestingly, their selection-adjusted CIs all include 1, which is consistent with the findings from the subsequent replication studies.
