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Chunk #21 — DISCUSSION

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Timing of first alcohol use and alcohol dependence: evidence of common genetic influences.
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Just over half of the variance in AD (53%) was accounted for by genetic factors, with the remainder explained by unique environmental factors. There was no evidence for shared environmental influences on AD. Our heritability estimate falls within the 50-60% range reported in the larger literature, which, like the current study, supports a model of alcohol dependence as a disorder shaped about equally by genetic and individual-specific environmental factors12,14-16.