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Chunk #6 — Introduction

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Alcohol use disorder is associated with altered frontomedial phase-amplitude coupling strength during resting state.
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Identifying new measures to characterize brain networks and functions underlying AUD will deepen our understanding of risk factors and resilience and enable designing effective treatments for AUD. While aberrant functional connectivity in the brain has been seen with fMRI and EEG coherence in AUD, the potential impacts of AUD on cross-frequency forms of functional connectivity like PAC have not yet been investigated.