The phenotype of antisocial features in the Health 2000 cohort was assessed with a scale, which is part of the home interview of the Health 2000 survey. The scale is originally from a 50-item scale, ‘Cook-Medley hostility scale',18, 19 and it included eight questions focusing on the aspects of deceitfulness, distrust to other people, and lack of empathy. Information on the childhood environment of economic difficulties or severe conflicts in the family were questioned and applied in gene-environment interaction analyses (Supplementary Information).