with associations between PRS and fronto-central (F3-C3 -- F7-T7, FZ-CZ -- F8-T8) coherence pairs only observed at ages 24–26. Results are detailed in Table 1. In PRS-EEG coherence association models including alcohol, nicotine, and cannabis use frequency as covariates, results were largely unchanged (see Supplemental material).Table 1First quartile of association beta coefficients and p-values of SCZ PRS with high-alpha EEG coherence in males and females ages 12–31 with −log10 transformation.Ages 12–17Ages 18–25Ages 26–31MaleFemaleMaleFemaleMaleFemaleFrontal-central sagittal−log10p-value−log10p-value−log10p-value1F8-T8--F7-T70.830.692.520.750.760.982F4-C4--F3-C32.350.691.340.531.881.173F3-C3--F8-T82.131.442.231.020.682.884F4-C4--F7-T70.560.611.520.510.710.415F3-C3--F7-T73.071.231.962.822.103.726F4-C4--F8-T80.580.721.001.001.931.947FZ-CZ--F7-T74.770.874.431.042.301.258FZ-CZ--F3-C33.972.412.851.242.621.099FZ-CZ--F8-T81.311.311.211.180.563.4110FZ-CZ--F4-C42.361.233.141.553.871.18Central-parietal sagittal11T8-P8--T7-P73.170.703.970.802.010.8712C4-P4--C3-P33.331.294.500.793.610.4413C3-P3--T8-P83.131.032.220.911.811.1414C4-P4--T7-P74.140.904.620.992.470.5215C3-P3--T7-P74.470.644.772.451.891.4916C4-P4--T8-P83.201.982.772.701.591.6117T7-P7--CZ-PZ3.091.175.151.542.871.1218C3-P3--CZ-PZ2.521.625.181.354.971.6219T8-P8--CZ-PZ1.770.912.101.190.930.5720C4-P4--CZ-PZ2.641.644.121.173.321.32Parietal-occipital sagittal21P4-O2--P3-O15.243.095.381.222.601.29Intrahemispheric lateral22T7-C3--F7-F30.660.842.480.994.872.5023P7-P3--F7-F31.560.561.640.941.870.8924P7-P3--T7-C34.930.972.991.313.551.8325T8-C4--F8-F41.141.862.731.312.371.1926P8-P4--F8-F44.360.443.641.551.791.6827P8-P4--T8-C46.420.764.562.012.432.16All values in bold meet the false-discovery rate criterion of 10−4. Coherences between bipolar electrode pairs are numbered from 1–27 and organized by regions as illustrated in Fig. 1 and explained in its caption.
